Top 10 Cool and Unusual Hotels in Greenville

Greenville beckons nature lovers to bask in the breathtaking beauty of the Blue Ridge Mountains and revel in small-town pleasures while healing in the unfiltered wilderness of South Carolina. Famous for its vibrant and historic downtown district, Greenville is an amazing pedestrian-friendly community, and walking is the best way to explore all its fascination-packed nooks and crannies.

From mesmerizing waterfalls and serene nature parks brimming with hiking and biking trails to beautifully manicured gardens, elegant restaurants, and modern entertainment venues, Greenville is one of the best destinations for a well-rounded experience. However, finding the right accommodation is important to experience the best of this quaint alpine town.

Our roundup of elegant boutique hotels, historic inns, charming farmhouse-style lodges, and world-class luxury brands will introduce you to the coolest hotels in Greenville, South Carolina (in no particular order)

Best For River Views

Grand Bohemian Lodge Greenville, Autograph Collection

Insta-worty Hotel Greenville

Beautiful Hotel Greenville

Instagrammable Hotel Greenville

Nestled in the core of Greenville’s alluring historic district, the Grand Bohemian offers magnificently appointed rooms with expansive floor-to-ceiling windows offering breathtaking views of Falls Park and downtown attractions.

This elegant lodge is perched beautifully along the scenic Reedy River, combining a serene setting with world-class amenities. Guests can book luxurious massages and beauty treatments at the in-house spa and enjoy sumptuous meals at the riverside restaurant.

The pet-friendly hotel rooms and suites are well-appointed with in-room appliances, finely crafted furniture, and ornate details. The interiors are a majestic feast of art and culture, featuring a lovingly curated collection of artworks, decorative chandeliers, and rich bohemian textures.


Scrumptious meals at the riverside restaurant

Offering breathtaking picturesque views of Falls Park

Sip freshly handcrafted cocktails and rare bourbon


Marginally expensive accommodation

Slight auditory disturbance noticed

Best For Rustic Chic Decor

Swamp Rabbit Inn

Unique Hotel Greenville Quirky-Chic Hotel Greenville

A European-style venue that radiates warmth and beauty with its period-themed interiors and brightly lit, airy spaces, the Swamp Rabbit Inn is situated in the heart of Greenville’s iconic West End neighborhood.

Travelers can explore beautifully designed rooms or rent the whole house for an upcoming wedding or extended staycation.

The Main House has an idyllic appeal with its centuries-old magnolia trees and four tastefully appointed guest rooms, titled Azalea, Camellia, Magnolia, and Poppy.

Families and groups seeking a private and intimate setting prefer the charming Coach House or the delightful 2-bedroom cottage with a sprawling porch. This cozy inn is a popular spot for adventurers embarking on the nearby Swamp Rabbit Trail.


Period-themed decor with bright well-lit open areas

Rent the whole house or just a room with a patio

Just a block off the Swamp Rabbit Trail


Some noise

Unregulated room temperature

Best For Gen-Z and Millennials

Aloft Greenville Downtown

Themed Hotel Greenville Hotel Perfect for Partying Greenville Hotel Aloft Greenville Downtown

Aloft Greenville beckons travelers with its central downtown location and brightly-lit interiors brimming with free-spirited energy. This modern hotel combines a sleek minimalist aesthetic with cutting-edge technology to offer its guests a laid-back and relaxing environment elevated by modern conveniences.

The hotel offers an array of mid-sized, queen, king, and deluxe accommodations, featuring fine-appointed furniture, in-room appliances, entertainment amenities, and luxurious bedding.

Guests enjoy mingling with locals and like-minded travelers at the hip WXYZ bar, popular for its flavorful cocktails and live music events.

Aloft provides a multitude of resort-like facilities, including an outdoor pool, lounging area, onsite gym, business center, event venues, meeting space, etc.


Play billiard or ride free bikes

A refreshing outdoor swimming pool

Outdoor fireplace and a snack bar

On-site temporary art galleries


Paid parking

Pets allowed for extra charges

Slightly noisy

Best For Great Breakfast

Greenville Marriott

Stylish Hotel Greenville Top rated Hotel Greenville

The Greenville Marriott is a world-class accommodation that curates an extravagant experience for its discerning patrons, offering them a unique taste of sumptuous luxury and innovative amenities.

This family-friendly hotel offers a delightful blend of traditional values, indulgent creature comforts, and tech-savvy convenience.

The well-appointed guest rooms and suites attract business and leisure travelers and families seeking top-of-the-line service and business-friendly amenities. The accommodations are tastefully furnished with custom-built furniture, in-room appliances, and luxe toiletries.

Guests enjoy the convenience of a 24-hour business center, a well-equipped fitness center, complimentary airport shuttle service, and an on-site dining spot, the Artisan Restaurant and Lounge.


A calm and quiet environment adds to the relaxation

Scrumptious morning meal overlooking the bay

Guests can use the outdoor pool and enjoy massages


Paid internet connection

Limited proactive engagement

Best For Southern Charm

The Westin Poinsett, Greenville

Historic Hotel Greenville Elegant Hotel Greenville Historic-Chic Hotel Hotel Greenville

One of the finest boutique hotels in downtown Greenville, The Westin Poinsett offers world-class opulence with tech-savvy amenities. This AAA Four-Diamond hotel is a stone’s throw away from the Peace Center, local retail hubs, and popular hangout spots.

Guests can explore a wide selection of tastefully decorated rooms and suites, featuring luxurious sleep stations, luxe bathrooms, in-room appliances, fine linens, and marble vanities.

The onsite WestinWorkout Fitness Studio is well-equipped for cardio and strength training, and guests can reserve the sprawling meeting areas and event space.

This upscale venue is a popular choice for weddings and corporate events, offering 10,000 square feet of elegantly appointed space to hold any gathering.


Room features 1920s-inspired with added comfort

Offers classic American cuisines for breakfast and cocktails

Featuring luxurious sleep stations and luxe bathrooms


Minor concerns regarding valet parking

Slight cleanliness concerns

Best For Luxury Seekers

The AC Hotel by Marriott Greenville

Design Hotel Greenville Modern-Chic Hotel Greenville

The AC Hotel is a remarkable project by the world-renowned Marriott brand, and it welcomes travelers to a classy venue with a fashionable address, the iconic Main Street. This central downtown accommodation pays homage to the art and cultural history of its surroundings with beautiful aplomb.

 The hotel is home to a beautifully curated collection of original artworks created by talented local artists. The well-appointed rooms and suites combine European-style elegance with indulgent creature comforts, curating a soothing space for weary travelers to relax and unwind.

The onsite dining establishment, Paloma, is one of the finest gems in Greenville’s vibrant food scene, serving a delectable fusion of American and Spanish cuisine.


Enjoy American and Mediterranean dishes and cocktails

Guests can enjoy hiking or cycling around the hotel

Ideal for sports-buff with Sirrine Football Stadium nearby


Paid parking only

Rollaway beds not available

Best For Swimming Pool

Hilton Garden Inn Greenville

Modern Hotel Greenville Hilton Garden Inn Hotel Greenville

An award-winning venue with a romantic setting, the Hilton Garden Inn pays homage to South Carolina’s stunning natural beauty and traditional hospitality. Guests can explore beautifully designed rooms and suites decked with luxurious bedding and modern amenities.

This 100% smoke-free hotel is a popular choice for discerning travelers who demand extensive personalization and rely on diligent staff to manage their needs. Guests staying at the Hilton Garden Inn typically begin their day with a cooked-to-order breakfast spread and end their sightseeing tours with lavish dinners at the onsite Garden Grille & Bar.

The central location is within walking distance of numerous popular attractions, including Greenridge, downtown Greenville, and the Mesa Complex.


Inviting and snug ambiance with a cozy vibe

A seasonal outdoor saltwater pool

A super cool patio for resting and relaxing


Paid public parking on-site

Slightly noisy at night time

Best For Onsite Dining

Tru By Hilton Greenville Woodruff Road, SC

Trendy Hotel Greenville

Funky hotel in Greenville

Tru By Hilton is a lively and upbeat accommodation for travelers looking to indulge in indulgent creature comforts and tech-savvy convenience.

This centrally located hotel is situated in the core of all the action and entertainment in Greenville’s downtown district, within proximity to Greenridge’s retail therapy and the breathtaking Reedy River Falls Park.

Tru offers an extensive selection of accommodations, ranging from small rooms and mid-sized suites to sprawling deluxe rooms and family-friendly suites.

Guests enjoy an array of luxury amenities and on-site facilities, including free WiFi, free parking, an onsite fitness studio, and an indoor pool.

The well-appointed lobby serves as a comfortable space to lounge, mingle, and work.


Free breakfast buffet daily with many options

Comfortable lounge with billiards for relaxation

Barbeque grill and fire pits to gather around and rest


Rather compact accommodation

Slight cleanliness concerns

Best For Longer Stays

stayAPT Suites Greenville-Haywood Mall

Affordable Suite Greenville Contemporary Suites Greenville

The ultimate spot for a staycation, StayAPT Suites offers travelers autonomy, independence, and a stellar location to explore Greenville’s popular sites. This apart-style hotel offers travelers elaborate workstations, luxuriously comfortable sleep stations, and laid-back dining spaces.

Guests enjoy privacy and independence in 500-square-foot suites featuring lavishly appointed bedrooms, comfortable living areas, fully-equipped kitchens, dining spaces, and designated workstations. Each space is furnished with tasteful furniture, smart appliances, and serene color palettes.

The accommodations come with a sprawling outdoor courtyard featuring a fire pit, built-in grill, and elegant seating – perfect for hosting BBQs. 


Lavish and comfortable environment

The courtyard features a fire pit and a built-in grill

Coffee Maker with complimentary starter pack


Pets are allowed subject to extra charges

Few kitchen accessories

Best For: Boutique

Urban Boutique Hotel; BW Signature Collection

Urban Hotel Greenville Affordable Hotel Greenville

An oasis of opulence and glamor, the Urban Boutique Hotel radiates the magnificence synonymous with the renowned Best Western brand. Perched elegantly on the foothills of the breathtaking Blue Ridge Mountains, this glamorous establishment combines a splendid location with traditional Southern hospitality and modern luxuries.

The Urban Boutique offers an extensive selection of elegantly designed rooms and suites, equipped with lavishly indulgent sleep stations, upscale amenities, in-room appliances, and fine linens.

The hotel is highly commended for its courteous staff and for maintaining the highest standards of hygiene and service with keen attention to detail. The location is amazingly convenient for enjoying Greenville’s natural beauty and being surrounded by over 100 cafes, bars, retail outlets, entertainment venues, and fine dining spots.


Free full continental breakfast and fresh fruit juices

Reasonable price with modern amenities

Surrounded by 100+ cafes and entertainment venues


Slight cleanliness concerns

Minor parking lot issues

Top 10 Best Hotels in Greenville Compared

Here is the tabular comparison of the top 10 cool and unusual hotels in Greenville.

Hotel NameLocationPrice Range (per night)Fitness FacilitiesDistance to Attractions (km)Nearby Restaurants
Grand Bohemian Lodge Greenville, Autograph Collection44 East Camperdown Way$380Yes1.03
Swamp Rabbit Inn1 Logan St--------
Aloft Greenville Downtown5 North Laurens Street$304-$329Yes1.03
Greenville MarriottOne Parkway East$160-$214Yes11.03
The Westin Poinsett, Greenville120 South Main Street$234-$352No0.952
The AC Hotel by Marriott Greenville315 South Main Street$315Yes0.43
Hilton Garden Inn Greenville108 Carolina Point Parkway$167-$217Yes7.53
Tru By Hilton Greenville Woodruff Road, SC121 Carolina Point Parkway$149Yes7.52
stayAPT Suites Greenville-Haywood Mall85 Mall Connector Road$125Yes5.13
Urban Boutique Hotel; BW Signature Collection536 Wade Hampton Blvd$78No2.22